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Species Comparison and Metabolite Profiling
The metabolic stability and metabolite profiling of the test item is investigated and compared with respect to different species in vitro. The data obtained provide valuable information for species selection in toxicological studies in vivo.
Available Species, Strains and Test Systems
| Species |
Liver Micorsomes |
Primary Hapatoctes |
| - |
- |
cyropreserved |
freshly isolated |
| Human |
individual donor
or pooled
(maled, female, mixed)
|
individual donor
or pooled
(male, female, mixed)
|
individual donor
(male, female)
|
| Rat |
Sprague Dawley
Fischer 344
Wistar
IGS Sprague Dawley
(male, female, mixed)
|
Sprague Dawley
Wistar
(male, female, mixed) |
Sprague Dawley
Fischer 344
IGS Sprague Dawley
(male, female, mixed) |
| Dog |
Beagle Dog
(male, female, mixed) |
Beagle Dog
(male, female, mixed) |
Beagle Dog
(male, female) |
| Guinea Pig |
Hartley Albino
(male) |
please inquire |
please inquire |
| Rabbit |
New Zealand
(male) |
New Zealand
(male, female, mixed) |
please inquire |
| Mouse |
CD1
B6C3F1
(male)
|
CD1
|
please inquire |
| Monkey |
Rhesus
Cynomolgus
(male, female, mixed)
|
Cynomolgus
(male, female, mixed)
|
(male, female) |
| Hamster |
Golden Syrian
(male) |
please inquire |
please inquire |
| Minipig |
please inquire
(male)
|
Gottingen Minipig |
individual animal |
Please inquire for other species and tissues, gender or induced animal products
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